6533b7cffe1ef96bd1258be8
RESEARCH PRODUCT
Phytochemistry of Weigela x "kosteriana variegata" (Caprifoliaceae)
N. AndriamisainaAnne Claire Mitaine-offerB. PruvotJ. ChlubaT. MiyamotoC. TanakaM. -A Lacaille-duboissubject
[SDV.AEN] Life Sciences [q-bio]/Food and NutritionWeigela x "kosteriana variegata"[SDV.SP.PHARMA] Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyZebrafish-based assay[SDV.SP.PHARMA]Life Sciences [q-bio]/Pharmaceutical sciences/PharmacologyOleanolic acid glycosides2D NMR[SDV.AEN]Life Sciences [q-bio]/Food and NutritionCaprifoliaceaedescription
International audience; One new triterpene glycoside 3-O-beta-D-xylopyranosyl-(1 -> 4)-[beta-D-glucopyranosyl-(1 -> 3)]-beta-D-xyl opyranosyl-(1 -> 4)-beta-D-xylopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyloleanolic acid, was isolated from Weigela x "kosteriana variegata" (Caprifoliaceae), with three known ones. Their structures were characterized by a combination of mass spectrometry and 1D and 2D NMR spectrocopic techniques including H-1- and C-13 NMR, COSY, TOCSY, NOESY, HSQC, and HMBC experiments. The toxicological properties of some glycosides were determined with a zebrafish-based assay. The results show that the most active compounds were toxic to the larvae in the range of 1 mu M.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-04-01 |