6533b7cffe1ef96bd1259a8b
RESEARCH PRODUCT
Evaluation of bleeding risk and measurement methods in dental patients
Ariadna García-herraizGuillermo CañigralFrancisco-javier SilvestreManuel AlósAranza CañigralAndres Plazasubject
AdultMalemedicine.medical_specialtyAdolescentOral Surgical ProceduresPostoperative HemorrhageRisk AssessmentYoung AdultInternal medicineAntithromboticHumansMedicineProspective StudiesYoung adultProspective cohort studyGeneral DentistryAgedAged 80 and overbusiness.industryIncidence (epidemiology)Middle Aged:CIENCIAS MÉDICAS [UNESCO]ClopidogrelSurgeryOtorhinolaryngologyHemostasisCohortUNESCO::CIENCIAS MÉDICASFemaleSurgerybusinessRisk assessmentmedicine.drugdescription
Objective: The present study explores bleeding manifestations in routine dental surgical procedures, evaluates the influence of antithrombotic drugs upon bleeding risk, and validates the efficiency of a clinical method for the measurement of bleeding. Material and method: A prospective observational study was made involving a cohort of 99 patients in the setting of normal clinical practice, with the added conduction of prior hematological tests including baseline hemostasis and platelet function, based on a new method (Multiplate System®). For evaluation of the bleeding manifestations, a clinical method was selected that evaluates bleeding on the basis of its duration and the hemostatic measures needed to resolve the problem. Results: Almost one-third of the patients (27.3%) were receiving treatment with oral antiplatelet drugs, while 19.2% received oral anticoagulants and 9% received combined therapy with acetylsalicylic acid plus clopidogrel. In turn, an 8% incidence of moderate bleeding episodes was detected correlated to the ASPI platelet function test and to advanced patient age. Conclusion: The incorporation of platelet function tests increases the safety of oral surgery in elderly patients subjected to antiplatelet treatment, particularly with acetylsalicylic acid and clopidogrel.
year | journal | country | edition | language |
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2010-02-27 |