6533b7d0fe1ef96bd125a259
RESEARCH PRODUCT
17O NMR study of isomeric monochloro- and monohydroxy-benzaldehydes and chlorinated salicylaldehydes
Erkki KolehmainenJuha Knuutinensubject
chemistry.chemical_classificationHydrogen bondChemical shiftchemistry.chemical_elementGeneral ChemistryNuclear magnetic resonance spectroscopyAldehydeMedicinal chemistryOxygenchemistryIntramolecular forceOrganic chemistryChemical solutionGeneral Materials Sciencedescription
The 17O NMR chemical shifts of isomeric monochloro- and monohydroxy-benzaldehydes and chlorinated salicylaldehydes were measured at 40°C for 0.25 M CDCI3 solutions. The 17O NMR chemical shift of the carbonyl oxygen of the compounds studied varies from 506 to 573 ppm measured from external D2O. The observed variation is probably mainly due to the intramolecular hydrogen bonding between the adjacent carbonyl and hydroxyl groups. The 17O NMR chemical shift range of the hydroxyl oxygen is from 80 to 98 ppm.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1991-05-01 | Magnetic Resonance in Chemistry |