Sun exposure and PDZK1 genotype modulate PDZK1 gene expression in normal skin

6533b7d0fe1ef96bd125a348

RESEARCH PRODUCT

Sun exposure and PDZK1 genotype modulate PDZK1 gene expression in normal skin

Gerard Pitarch Conrado Martinez-cadenas Gloria Ribas Laura Mahiques Barbara Hernando Maider Ibarrola-villava Francisca Valcuende-cavero Sara S. Oltra

subject

Keratinocytes Regulation of gene expression Genotype integumentary system Epidermis (botany)Immunology Membrane Proteins Dermatology General Medicine Biology Molecular biology Gene Expression Regulation Polymorphism (computer science)Genotype Sunlight Humans Immunology and Allergy Radiology Nuclear Medicine and imaging sense organs Sun exposure PDZK1 gene Normal skin Skin

description

Human skin pigmentation results from the enzymatically controlled synthesis of melanin pigments in specialized organelles (melano‐somes) produced within epidermal melanocytes, followed by their transfer to neighboring keratinocytes and their distribution through‐out the epidermis.1 Constitutive skin pigmentation seems to be mostly genetically determined,2 being altered by numerous intrinsic and extrinsic factors affecting the epidermal melanin unit

year	journal	country	edition	language
2020-01-01	Photodermatology, Photoimmunology & Photomedicine

https://doi.org/10.1111/phpp.12508

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