6533b7d0fe1ef96bd125a3b1
RESEARCH PRODUCT
Immunologic Effects of Interferon
Jürgen Knopsubject
InflammationInterleukin 2Immunity CellularMacrophagesCellAntigen presentationCell BiologyDermatologyBiologyBiochemistryInterferon-gammamedicine.anatomical_structureImmune systemInterferonImmune SystemImmunologymedicineAnimalsHumansMacrophageTumor necrosis factor alphaInterferonsMolecular Biologymedicine.drugInterferon regulatory factorsdescription
Interferons can be defined as a family of induced proteins sharing the capacity to exert pleiotropic effects on cell functions and to render cells resistant to virus infection. They are activating genes coding for a number of enzymes, most of which have not yet been characterized, and also by enhancing the synthesis of cell surface components. This enables interferons to modulate the immune response at different levels. This article will focus on the effects of interferon on antigen presentation, regulation of the immune response, activation of macrophage functions, and on its role in the pathogenesis of some diseases.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1990-12-01 | Journal of Investigative Dermatology |