6533b7d0fe1ef96bd125a4d7

RESEARCH PRODUCT

Hemodynamic effects of experimental testicular torsion.

W. GrimmG. JanetschekM. MarbergerF. Schreckenberg

subject

NephrologyMaleendocrine systemmedicine.medical_specialtyUrologyInfarctionHemodynamicsHemorrhageSpermatic cordInternal medicineTestismedicineTesticular torsionAnimalsHumansSpermatic Cord TorsionClinical significancecardiovascular diseasesSpermatic Cord Torsionbusiness.industryTunica vaginalisHemodynamicsRats Inbred StrainsArteriesmedicine.diseaseRatsDisease Models Animalmedicine.anatomical_structureInfarctionAnesthesiacardiovascular systemCardiologybusiness

description

Experimental testicular torsion must be used for certain studies of clinical relevance, but most experimental models either do not provide hemodynamic alteration comparable to the clinical situation or cannot guarantee reproducibility. Using a rat model arterial perfusion and hemorrhagic infarction were correlated to the degree of both intra- and extravaginal testicular torsion. Arterial inflow was measured sequentially with radiolabelled microspheres, hemorrhagic infarction was judged by the increase of testicular weight. Maximal hemorrhagic infarction and reproducible values were found when the spermatic cord was twisted together with the tunica vaginalis for 360 degrees-540 degrees.

10.1007/bf00258201https://pubmed.ncbi.nlm.nih.gov/3686761