6533b7d0fe1ef96bd125a5a0

RESEARCH PRODUCT

Marine Pyrrole Alkaloids

Kevin SeippTill OpatzLeander Geske

subject

Aquatic OrganismsQH301-705.5Ecologymarine natural productsPharmaceutical Sciencepyrrole-aminoimidazole alkaloidsReviewBiologyalkaloidsStructure-Activity Relationshipchemistry.chemical_compoundchemistrypyrrolesDrug DiscoveryAnimalspyrrole-imidazole alkaloidsnitrogen heterocyclesbromopyrrolesBiology (General)Pharmacology Toxicology and Pharmaceutics (miscellaneous)Pyrrole

description

Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal intriguing structures. They are not only widespread in terrestrial habitats but can also frequently be found as natural products in the marine environment. This review highlights the important class of marine pyrrole alkaloids, well-known for their diverse biological activities. A broad overview of the marine pyrrole alkaloids with a focus on their isolation, biological activities, chemical synthesis, and derivatization covering the decade from 2010 to 2020 is provided. With relevant structural subclasses categorized, this review shall provide a clear and timely synopsis of this area.

yearjournalcountryeditionlanguage
2021-09-10Marine Drugs
https://doi.org/10.3390/md19090514