6533b7d0fe1ef96bd125ab8a
RESEARCH PRODUCT
Flow injection-spectrophotometric determination of cresol compounds in water by reaction withp-aminophenol
ÁNgel Morales-rubioM. De La GuardiaKarim D. KhalafB. A. Hasansubject
Detection limitFlow injection analysisChromatographymedicine.diagnostic_testo-CresolCresolAnalytical ChemistryAbsorbancechemistry.chemical_compoundchemistrySpectrophotometryparasitic diseasesOxidizing agentmedicineDerivatizationmedicine.drugdescription
A spectrophotometric method has been developed for the simultaneous determination ofo-cresol andm-cresol in water by reaction withp-aminophenol (PAP). Three different methodologies have been assayed; (i) batch analysis, after reaction in an alkaline medium in the presence of dissolved molecular oxygen as oxidizing agent, (ii) a stopped-flow procedure, carried out in the presence of KIO4 and (iii) a flow injection method based on the same approach. The batch procedure requires 22 min for the full development of colour witho-cresol and 12 min form-cresol. In the stopped-flow mode, using KIO4 and a reaction time of 12 min, better sensitivity can be obtained for both compounds and limits of detection of 10 μg 1−1 foro-cresol and 30 μg 1−1 form-cresol were found. The flow injection method has a lower sensitivity but permits more than 80 injections per hour. Based on the different maximum absorbance wavelengths obtained for the reaction products of PAP witho-cresol (614 nm) andm-cresol (632 nm), both compounds can be simultaneously determined in water samples and recoveries of 90 to 115% were found in spiked water samples of different types.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1993-01-01 | Microchimica Acta |