6533b7d0fe1ef96bd125ad01
RESEARCH PRODUCT
Glial Protection Against Neuronal Damage
O. KempskiC. Volksubject
Glutamate uptakeCytosolnervous systemChemistryNeuronal damageIschemiamedicineGlutamate receptorExtracellularNeuronal protectionmedicine.diseaseHomeostasisCell biologydescription
Glial homeostatic mechanisms are involved in neuronal protection during the early phase of cerebral ischemia. These protective effects include, among others, glutamate uptake and the regulation of pH in the extracellular space of the brain. Uptake of glutamate goes along with glial swelling, as does the elimination of protons from the glial cytosol. Five transport systems interact in order to maintain a normal intra- and extracellular pH in the brain.
year | journal | country | edition | language |
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1997-01-01 |