6533b7d0fe1ef96bd125b5da

RESEARCH PRODUCT

Stereocontrolled approach to quinuclidine derivatives

Jean D'angeloAlexandre J. Da Silva GoesChristian CavéChristian Cavé

subject

chemistry.chemical_compoundDegree (graph theory)Derivative (finance)ChemistryStereochemistryOrganic ChemistryDrug DiscoveryStereoselectivityBiochemistryQuinuclidine

description

Abstract Asymmetric Michael-type cyclization of chiral enamino ester (S)-7 furnished the quinuclidinone derivative (3R, 4S)-5, with a high degree of stereoselectivity.

https://doi.org/10.1016/s0040-4039(97)10812-7