6533b7d0fe1ef96bd125b722
RESEARCH PRODUCT
Diepoxyrollin and Diepomuricanin B: Two New Diepoxyacetogenins from Rollinia membranacea Seeds
Jairo SaezSevser SahpazDiego CortesReynald HocquemillerAndré Cavésubject
Pharmacologychemistry.chemical_classificationRollinia membranaceabiologyStereochemistrySylvaticinOrganic ChemistryPharmaceutical SciencePharmacognosybiology.organism_classificationAnalytical ChemistryComplementary and alternative medicinechemistryAnnonaceaeDrug DiscoveryMolecular MedicineAnnonaceous AcetogeninsSpectral dataLactonedescription
Diepoxyrollin (1) and diepomuricanin B (2), two new Annonaceous acetogenins were isolated from the cytotoxic MeOH extract of the seeds of Colombian Rollinia membranacea. Five others known acetogenins were also isolated, dieporeticanin 1, dieporeticanin 2, diepomuricanin A, rollinone, and sylvaticin. Their structures were elucidated on the basis of spectral data. Compounds 1 and 2 belong to the rare type of diepoxyacetogenins, which are probably precursors of the mono-tetrahydrofuran acetogenins.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1997-02-01 | Journal of Natural Products |