6533b7d0fe1ef96bd125b9dd
RESEARCH PRODUCT
On the genetics of the pi serum proteins.
H. WalterG. Kellermannsubject
GeneticsMaleInheritance (genetic algorithm)NorwegianPi phenotypesBiologymedicine.disease_causelanguage.human_languageHuman geneticsFamily studiesGenetics PopulationPhenotypeHeredityGeneticslanguagemedicinePiHumansFemaleAlleleTrypsin InhibitorsGenetics (clinical)Allelesdescription
The authors report family studies (51 families with 134 children) on the inheritance of the Pi phenotypes. Combining these data with a Norwegian family material (77 families with 323 children) published by Fagerhol and Gedde-Dahl (1969) a total of 128 families with 457 children is now available, which allows the following conclusion: The Pi phenotypes are inherited by a simple codominant mode of heredity and they are determined by a set of (at least nine) alleles. As up to now no exception to the role of inheritance has been observed, the application of the Pi system in cases of disputed paternity seems to be discussible. Some methodological problems in connection with this are shown.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1970-09-17 | Humangenetik |