6533b7d1fe1ef96bd125bb1f

RESEARCH PRODUCT

Investigation of fungicidal activity of 3-piperazine-bis(benzoxaborole) and its boronic acid analogue

subject

fungicidal activitybenzoxaborolesboronic acidsfungicides

description

3-Piperazine-bis(benzoxaborole) and its bis(phenylboronic acid) analogue were investigated in terms of their fungicidal activity. The study was carried out against five filamentous fungi: Aspergillus terreus, Fusarium dimerum, Fusarium solani, Penicillium ochrochloron and Aspergillus niger. 3-Piperazine-bis(benzoxaborole) revealed higher inhibitory activity towards the examined strains than standard antibiotic (amphotericin B), whereas bis(phenylboronic acid) proved to be inactive. The study unequivocally showed that the presence of the heterocyclic benzoxaborole system is essential for antifungal action of the examined compounds.

10.1002/aoc.3132https://doi.org/10.1002/aoc.3132