6533b7d1fe1ef96bd125c29c

RESEARCH PRODUCT

Blood group does not appear to affect longevity a pilot study in centenarians from Western Sicily.

Giovanni DuroLaura CastigliaClaudia RizzoCalogero CarusoRoberto MonasteroSonya Vasto

subject

GerontologyMaleAgingmedia_common.quotation_subjectPopulationLongevityBiologyABO Blood-Group SystemABO blood group systemABO Centenarian Genotyping Immunogenetics LongevitymedicineHumansAlleleeducationGenotypingSicilymedia_commonAgedSettore MED/04 - Patologia GeneraleAged 80 and overeducation.field_of_studyLongevityCancerMiddle Agedmedicine.diseaseCase-Control StudiesLife expectancySettore MED/26 - NeurologiaFemaleGeriatrics and GerontologyCentenarianGerontologyDemography

description

Centenarians are the best example of extreme human longevity, and they represent a selected population in which the appearance of major age-related diseases, such as cancer, and cardiovascular diseases among others, has been consistently delayed or escaped. The study of the long-lived individual genetic profile has the purpose to possibly identify the genes and the allelic variations influencing extended life expectancy, hence considering them as biomarkers of age-related diseases onset and development. The present study shows no significant differences between allelic variations of ABO blood groups among a group of centenarians from Western Sicily.

yearjournalcountryeditionlanguage
2011-06-07Biogerontology
10.1007/s10522-011-9350-7https://pubmed.ncbi.nlm.nih.gov/21766224