Foci of degeneration produced by measles virus in cell cultures with antibody-free liquid medium

6533b7d1fe1ef96bd125c3f9

RESEARCH PRODUCT

Foci of degeneration produced by measles virus in cell cultures with antibody-free liquid medium

Francesca Ajello Pietro Brancato M. Fatima Massenti

subject

Microbiology (medical)medicine.medical_specialty Immunology Kidney Measles Antibodies Virus Measles virus HeLa Medical microbiology medicine Animals Humans Immunology and Allergy Cells Cultured Bacteriological Techniques biology Immune Sera Haplorhini General Medicine medicine.disease biology.organism_classification Virology In vitro Culture Media Measles virus Cell culture biology.protein Female Antibody HeLa Cells

description

Measles virus produces discrete foci of degeneration in monkey kidney cell and HeLa cell cultures with antibody-free liquid medium. The number of sharply defined “foci” is directly proportional to the relative virus dilution. The technique for enumeration of infective units of measles virus by “foci” count is described. The self-limiting spread of measles virusin vitro and some possible advantages over the standard plaque method are discussed.

year	journal	country	edition	language
1974-01-01	Medical Microbiology and Immunology

https://doi.org/10.1007/bf02123724

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