6533b7d1fe1ef96bd125c49d
RESEARCH PRODUCT
Mannitol in Amanita muscaria – An osmotic blood–brain barrier disruptor enhancing its hallucinogenic action?
Ewa MaciejczykPaweł Kafarskisubject
HallucinogenMagnetic Resonance SpectroscopyInjury controlAmanitaPoison controlComplex MixturesPharmacologyBlood–brain barrierToxicologyOsmoregulationSpecies SpecificityHumansMedicineIngestionMannitolbiologybusiness.industryAgaricBrainGeneral Medicinebiology.organism_classificationmedicine.anatomical_structureHallucinogensMannitolbusinessAmanita muscariamedicine.drugdescription
Hypothesis have been made that relatively high level of mannitol present in the tissues of fly agaric (Amanita muscaria) enables more efficient transportation of these active substances into the brain and thus enhance their total activity. It may have been supported by the fact that hallucinogenic effect after A. muscaria consumption is greater than after ingestion of an active substance quantity which the eaten fungi dose contain.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2013-05-10 | Medical Hypotheses |