Synthesis of pyrrolo[3′,4′:2,3]azepino[4,5,6-cd]indole-8,10-diones

6533b7d1fe1ef96bd125cb75

RESEARCH PRODUCT

Synthesis of pyrrolo[3′,4′:2,3]azepino[4,5,6-cd]indole-8,10-diones

Markus Koller Siavosh Mahboobi Dieter Schollmeyer Alfred Popp Stella Eluwa

subject

Indole test Chemistry Yield (chemistry)Organic Chemistry Medicinal chemistry

description

3-Amino-4-(3-indolyl)pyrrolin-2,5-diones are condensed with various aldehydes and ketones to the cor responding imines. Under Pictet-Spengler conditions, the latter do not cyclize to pyrrolo-β-carbolines, but readily yield pyrrolo[3′,4′:2,3]azepino[4,5,6-cd]indole-8,10-diones.

year	journal	country	edition	language
2000-09-01	Journal of Heterocyclic Chemistry

https://doi.org/10.1002/jhet.5570370526

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