6533b7d1fe1ef96bd125cc6a

RESEARCH PRODUCT

A Comparison of Objective Physical Performance Tests and Future Mortality in the Elderly People.

Brendon StubbsBrendon StubbsStefania MaggiNicola VeroneseGiuseppe SergiS ZambonS ZambonLeonardo SartoriEstella MusacchioEnzo ManzatoEnzo ManzatoMaria Chiara CortiLuigi FontanaLuigi FontanaMarina De RuiCaterina TrevisanFrancesco BolzettaGaetano CrepaldiEgle Perissinotto

subject

Malemedicine.medical_specialtyAgingMortality—Physical activity—Physical performancePoison controlPhysical examinationNOPhysical performance03 medical and health sciences0302 clinical medicinePredictive Value of TestsInjury prevention80 and overMedicineHumans030212 general & internal medicineMortalityMortality; Physical activity; Physical performance; Aged; Aged 80 and over; Female; Geriatric Assessment; Humans; Male; Mortality; Physical Examination; Predictive Value of Tests; Prognosis; Aging; Geriatrics and GerontologyGeriatric AssessmentPhysical ExaminationAgedMortality; Physical activity; Physical performanceAged 80 and overmedicine.diagnostic_testbusiness.industryPhysical activityConfoundingPrognosisConfidence intervalPreferred walking speedQuartilePredictive value of testsPhysical therapyFemaleGeriatrics and Gerontologybusinesshuman activities030217 neurology & neurosurgery

description

Background: Physical performance is an important predictor of mortality, but little is known on the comparative prognostic utility of different objective physical performance tests in community-dwelling older adults. We compared the prognostic usefulness of several objective physical performance tests on mortality, adjusting our analyses for potential confounders. Methods: Among 3,099 older community-dwelling participants included in the Progetto Veneto Anziani study, 2,096 were followed for a mean of 4.4 years. Physical performance tests measured were Short Physical Performance Battery (SPPB), 4-meter gait speed, chair stands time, leg extension and flexion, handgrip strength, and 6-Minute Walking Test (6MWT), treated as continuous variables and categorized in genderspecific quartiles. The main outcome was mortality assessed with death certificates. Results: Participants who died during the follow-up (n = 327) scored significantly worse in all physical performance tests measured at baseline than those who survived (n = 1,769). Using a Harrell's C-index, the highest C-index was observed for 6MWT in men (C-index = 0.735; 95% confidence interval [CI]: 0.701-0.770, p < .0001) and SPPB in women (C-index = 0.781; 95% CI: 0.740-0.822, p = .0009). However, in both genders, only SPPB, 4-meter walking speed, and 6MWT are significant predictors of mortality. Analyses using sex-specific quartiles substantially confirmed these findings. Conclusions: Slow gait speed, 6MWT, and SPPB are significant predictors for mortality in community-dwelling older men and women. Physicians should consider using these tests to identify elderly individuals who are at higher risk of death to improve clinical decision making. © The Author 2016.

yearjournalcountryeditionlanguage
2017-01-01
http://europepmc.org/abstract/med/27470299