6533b7d1fe1ef96bd125cdfc

RESEARCH PRODUCT

Primary Mucinous Adenocarcinoma of the Urinary Bladder with Signet-Ring Cells: Description of an Uncommon Case and Critical Points in Its Management

Giuliano Amorim AitaDaniele Amorim AitaFabrizio Di Maida

subject

Pathologymedicine.medical_specialtyUrinary bladderSignet ring cellSystemic chemotherapybusiness.industryRetroperitoneal Lymph Node030232 urology & nephrologyCase ReportGeneral Medicinemedicine.diseaselcsh:Diseases of the genitourinary system. Urologylcsh:RC870-92303 medical and health sciences0302 clinical medicinemedicine.anatomical_structure030220 oncology & carcinogenesismedicineAdenocarcinomaImmunohistochemistryProstate glandbusiness

description

We present an uncommon case of mucinous adenocarcinoma of the bladder (MAB) with signet-ring cells extensively infiltrating prostate gland and pelvic/retroperitoneal lymph node stations and not responsive to usual systemic chemotherapy regimens. This case highlights the important features of MAB including the pattern of tumor spread, the tendency for initial misdiagnosis, and the importance of immunohistochemical study in order to define its primary origin from the bladder and choose the most appropriate treatment since the beginning.

10.1155/2016/6080859https://doaj.org/article/c2e72a9a43ff4378bb861d7f34cd8b9d