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RESEARCH PRODUCT
Molecular Alterations of the RBI, TP53, and MDM2 Genes in Primary and Xenografted Human Osteosarcomas
Carmen CardaTimoty J. TricheJavier Boix-ferreroDolores Lopez-terradaAntonio PellínDominica CarpioSamuel NavarroAntonio Llombart-boschAmando Peydro-olayasubject
Primary (chemistry)Cell cultureCancer researchbiology.proteinMdm2Cell BiologyBiologyneoplasmsMolecular BiologyGenePathology and Forensic Medicinedescription
We report the status of the RBI, TP53, and MDM2 genes in human osteosarcomas and cell lines established from surgical specimens and transplanted into athymic naked mice. By using reverse transcriptase-polymerase chain reaction (RT-PCR) as a prescreening technique and posterior sequencing, we observe
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1997-12-01 | Diagnostic Molecular Pathology |