6533b7d2fe1ef96bd125dd2b

RESEARCH PRODUCT

Environment and Endometriosis: A toxic relationship

I. SoaveD. CasertaJ. -M WengerS. DessoleA. PerinoRoberto Marci

subject

ddc:616DioxinPolychlorinated Biphenyls/toxicityddc:618Endometriosis Environment Dioxin Dioxin-like compounds.Endometriosisanimals; dioxins; endometriosis; environmental exposure; female; humans; polychlorinated biphenylsEnvironmental ExposureEnvironmentDioxinsPolychlorinated BiphenylsSettore MED/40 - Ginecologia E OstetriciaEndometriosis/etiology/pathologyNODioxin-like compoundsAnimalsHumansFemaleDioxins/toxicityEnvironmental Exposure/adverse effectsDioxin; Dioxin-like compounds; Endometriosis; Environment

description

Endometriosis is a common, be- nign, estrogen-dependent gynecological dis- ease that represents one of the main causes of hospitalization in industrialized countries. It is well established that a large amount of natural and man-made chemicals are present in the en- vironment and both humans and animals are exposed to them. Dioxin and dioxin-like com- pounds have long biological half-life, can accu- mulate within the organism and could negative- ly affect several physiological processes. The purpose of this review is to provide an overview of the possible relationship between these chemicals and the pathogenesis of en- dometriosis.

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