6533b7d2fe1ef96bd125e136

RESEARCH PRODUCT

Pathophysiology of Campylobacter jejuni infections of humans.

Martin J. BlaserTrudy M. Wassenaar

subject

biologyVirulenceCampylobacterImmunologyVirulenceDiseasebiology.organism_classificationmedicine.disease_causemedicine.diseaseMicrobiologyCampylobacter jejuniMicrobiologyEnteritisCampylobacter jejuniInfectious DiseasesImmune systemGenotypeImmunologyCampylobacter InfectionsmedicineAnimalsHumansOrganism

description

Campylobacter jejuni and closely related organisms are major causes of human bacterial enteritis. These infections can lead to extraintestinal disease and severe long-term complications. Of these, neurological damage, apparently due to the immune response of the host, is the most striking. This review examines current knowledge of the pathophysiology of the organism. Diversity of C. jejuni isolates in genotypic and phenotypic characteristics now is recognized and clinically relevant examples are presented. Expected future directions are outlined.

yearjournalcountryeditionlanguage
2000-01-05Microbes and infection
10.1016/s1286-4579(99)80520-6https://pubmed.ncbi.nlm.nih.gov/10617934