6533b7d2fe1ef96bd125e172
RESEARCH PRODUCT
Lessons from Sicilian centenarians for anti-ageing medicine. The Oxi-inflammatory status
Calogero CarusoGiulia AccardiAnna AielloAnna CalabròMattia E LigottiGiuseppina Candoresubject
InflammationSettore MED/04 - Patologia GeneraleOxidative stressCentenariansLongevityGeneral Earth and Planetary SciencesGeneral Environmental Sciencedescription
Population ageing is a great achievement of humanity, but it also represents a challenge that the Western world is currently facing, as ageing is associated with increased susceptibility to age-related inflammatory diseases. Therefore, it is necessary to fully understand the mechanisms of healthy ageing to prevent the harmful aspects of ageing. The study of long living individuals (LLIs) is a great model for trying to achieve this goal. Accordingly, the oxy-inflammatory status of Sicilian LLIs was reviewed in the present paper. Based on the reported data, anti-inflammatory and anti-oxidative stress strategies have been discussed, useful for delaying or avoiding the onset of age-related diseases, thus favouring a healthy ageing process.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-09-26 | Translational Medicine @ UniSa |