6533b7d2fe1ef96bd125e225

RESEARCH PRODUCT

Examination and treatment of sleep-related painful erections--a case report.

A. SteigerOtto Benkert

subject

AdultMalemedicine.medical_specialtySedationAdministration OralPainElectroencephalographyArts and Humanities (miscellaneous)DibenzazepinesSleep Initiation and Maintenance DisordersInsomniamedicineHumansAmitriptylinePsychiatryClozapineEvoked PotentialsGeneral PsychologyClozapinemedicine.diagnostic_testPenile ErectionElectroencephalographyTrimipramineNocturnal penile tumescenceAnesthesiaDisturbed sleep patternSleep Stagesmedicine.symptomPsychologymedicine.drug

description

The case of a patient with sleep-related painful erections is described. Insomnia and a slight depressive syndrome occurred along with a long history of this disorder. No physical abnormality was found. At a baseline recording of sleep electroencephalography (EEG) and nocturnal penile tumescence (NPT), a disturbed sleep pattern and impaired NPT were recorded. Attempts to treat the disorder with diazepam, amitriptyline, trimipramine, and biperidene did not prompt a stable improvement of the disorder, but a dosage of 25 mg clozapine was sufficient to achieve normalized sleep architecture, remission of the depressive symptomatology, and normalization of NPT. It is likely that marked sedation is the mode of action of clozapine.

yearjournalcountryeditionlanguage
1989-06-01Archives of sexual behavior
10.1007/bf01543200https://pubmed.ncbi.nlm.nih.gov/2751420