6533b7d2fe1ef96bd125e2ca
RESEARCH PRODUCT
Solubility and solvation features of native cyclodextrins in 1-ethyl-3-methylimidazolium acetate
Alessandro TrioloFabrizio Lo CelsoJavier PerezOlga Russinasubject
CyclodextrinsPolymers and Plasticscyclodextringreen chemistrysolubilityOrganic ChemistryIonic liquids Solvation Hydrophobic solvation Cyclodextrin Emerging task specific solvents Sustainability Molecular dynamics Hydrogen bondingMaterials ChemistryImidazolesSolventsiONIC lIQUIDS cyclodextrin solubility green chemistryiONIC lIQUIDSSettore CHIM/02 - Chimica Fisicadescription
The comprehension of the mechanism entailing efficient solvation of cyclodextrins (CD) by green solvents is of great relevance to boost environmentally sustainable usages of smart supramolecular systems. Here, 1-ethyl-3- methylimidazolium acetate, an ecofriendly ionic liquid (IL), is considered as an excellent solvent for native CDs. This IL efficiently dissolves up to 40 wt.% β- and γ-CD already at ambient temperature and X-ray scattering indicates that CDs do not tend to detrimental flocculation under these drastic concentration conditions. Simu- lation techniques reveal the intimate mechanism of CD solvation by the ionic species: while the strong hydrogen bonding acceptor acetate anion interacts with CD's hydroxyl groups, the imidazolium cation efficiently solvates the hydrophobic CD walls via dispersive interactions, thus hampering CD's hydrophobic driven flocking. Overall the amphiphilic nature of the proposed IL provides an excellent solvation environment for CDs, through the synergic action of its components.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2022-05-16 |