6533b7d2fe1ef96bd125e9c6

RESEARCH PRODUCT

Effects on Arterial Blood Pressure of Methanol and Dichloromethanol Extracts fromJuniperus oxycedrus L.

R. BelloE. Primo-yuacuteL. MorenoJuan V. EspluguesBelén Beltrán

subject

PharmacologyTraditional medicinebiologybusiness.industryHypotensive drugAdrenergicHemodynamicsBiological activityPharmacognosybiology.organism_classificationchemistry.chemical_compoundBlood pressurechemistryMedicineMethanolbusinessJuniperus oxycedrus

description

The present study analysed the effect of the methanol and dichloromethanol extracts from Juniperus oxycedrus on arterial blood pressure in anaesthetized rats. The arterial blood pressure of normotensive rats was significantly reduced by the i.v. administration of both extracts. The hypotensive effect of these extracts was independent of the adrenergic system. These results may explain the vasorelaxing actions observed in other Juniperus species.

https://doi.org/10.1002/(sici)1099-1573(199703)11:2<161::aid-ptr57>3.0.co;2-c