6533b7d2fe1ef96bd125ea0c
RESEARCH PRODUCT
Stoichiometric and kinetic study of the 99Tc-DMSA complex obtained with stannous excess: A possible model for the physico-chemical behaviour of the radiopharmaceutical 99mTc-DMSA
Jorge GalvezJ.l. MorenoR. Garciasubject
RadiationNuclear Energy and EngineeringOxidation stateChemistry99mTc-DMSAInorganic chemistryAnalytical chemistrySN2 reactionRadiology Nuclear Medicine and imagingKinetic energyStoichiometrydescription
A stoichiometric and kinetic study was made of the 99mTc-DMSA complex obtained in the presence of large amounts of Sn2+. It is demonstrated that the Tc oxidation state is 3+. It is established that the complex degrades to another one if there is an Sn2+ deficiency. These results were confirmed by spectroscopic and spectrophotometric methods.
year | journal | country | edition | language |
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1982-07-01 | The International Journal of Applied Radiation and Isotopes |