6533b7d2fe1ef96bd125ebfb

RESEARCH PRODUCT

Plasma Metabolites Associated with Coffee Consumption: A Metabolomic Approach within the PREDIMED Study

Courtney DennisEstefanía ToledoEstefanía ToledoDolores CorellaDolores CorellaAmy DeikRamon EstruchRamon EstruchJosé LapetraMarta Guasch-ferréMarta Guasch-ferréMarta Guasch-ferréJordi Salas-salvadóJordi Salas-salvadóPablo Hernández-alonsoPablo Hernández-alonsoClary B. ClishLiming LiangLiming LiangEdward YuCristina Arazola RuanoCristina Arazola RuanoChristopher PapandreouChristopher PapandreouMiguel A. Martínez‐gonzálezMiguel ÁNgel Martínez-gonzálezMiguel ÁNgel Martínez-gonzálezFrank B. HuFrank B. HuEmilio RosEmilio RosMònica BullóMònica BullóCristina RazquinCristina RazquinMiquel FiolMiquel FiolMontserrat FitóFernando ArósMiguel Ruiz-canelaMiguel Ruiz-canela

subject

0301 basic medicinePREDIMEDMalehumanosestudios de casos y controlescoffeeLibrary sciencelcsh:TX341-641030209 endocrinology & metabolismCoffee consumptionCoffeeArticleCohort Studies03 medical and health sciencesPlasma0302 clinical medicineCoffeescafeínaPolitical scienceCaffeinemetabolómicaHumansMetabolomicsestudios de cohortesmediana edadplasmaAgedanciano030109 nutrition & dieteticsNutrition and DieteticscaféMiddle AgedPredimedPredimedmetabolomicsCross-Sectional StudiesCase-Control StudiesChristian ministryFemalelcsh:Nutrition. Foods and food supplyestudios transversalesFood Science

description

Few studies have examined the association of a wide range of metabolites with total and subtypes of coffee consumption. The aim of this study was to investigate associations of plasma metabolites with total, caffeinated, and decaffeinated coffee consumption. We also assessed the ability of metabolites to discriminate between coffee consumption categories. This is a cross-sectional analysis of 1664 participants from the PREDIMED study. Metabolites were semiquantitatively profiled using a multiplatform approach. Consumption of total coffee, caffeinated coffee and decaffeinated coffee was assessed by using a validated food frequency questionnaire. We assessed associations between 387 metabolite levels with total, caffeinated, or decaffeinated coffee consumption (&ge

yearjournalcountryeditionlanguage
2019-05-08
https://hdl.handle.net/10171/57780