6533b7d2fe1ef96bd125ece1
RESEARCH PRODUCT
An infrared spectroscopic tool for process monitoring: sugar contents during the production of a depilatory formulation.
Miguel De La GuardiaSalvador GarriguesJulia KuligowskiMercedes Cascantsubject
SucroseChromatographyChemistry PharmaceuticalAnalytical chemistryCarbohydratesInfrared spectroscopyWaterFructoseMaltoseAnalytical Chemistrychemistry.chemical_compoundchemistryScientific methodMultivariate AnalysisSpectroscopy Fourier Transform InfraredMaltotrioseLeast-Squares AnalysisSugarSpectroscopydescription
Abstract A fast, reliable and economical methodology has been developed to control the production process of sugar-based depilatories. The method is based on the use of attenuated total reflectance—Fourier transform infrared (ATR-FTIR) spectroscopy in combination with multivariate data analysis. A very simple sample preparation process involving the dissolution of samples in water was applied. Employing a multivariate calibration model established from data of 15 well characterized samples, prediction errors equal or below 3.04 mg mL−1 for the quantitative determination of fructose, glucose, sucrose, maltose and maltotriose were obtained. Results found in this preliminary study indicate a great potential for the development of at-line ATR-FTIR-PLS methods based on a careful selection of variables from IR spectra, delivering fast and reliable results. As a reference method, a liquid chromatography (LC)–IR method was adapted for sample characterization.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2012-09-01 | Talanta |