6533b7d2fe1ef96bd125f595

RESEARCH PRODUCT

The influence of comorbidities on the aging males' symptoms scale in patients with erectile dysfunction.

subject

description

To investigate if certain common age-related comorbidities are related with a positive aging males' symptoms (AMS) test outcome.This was a multicentric, transversal, observational study carried out in a male population with erectile dysfunction. Comorbidities and testosterone levels were registered. The relationship between comorbidities, testosterone levels, and the AMS test outcomes was studied using the global score and the sub-scale score components.The study included 1112 patients. In the multivariate analysis the global score strongly correlated with TT  12 nmol/L (odds ratio [OR] = 3.17; p  0.05), psychiatric disorders (OR = 2.73), dyslipidemia (OR = 2.07) and diabetes mellitus (OR = 1.64); the somatic sub-component was related to obesity (OR = 8.62), dyslipidemia (OR = 2.2) and TT  12 nmol/L (OR = 2.09); the psychogenic sub-component correlated with psychiatric disorders (OR = 3.73), stress (OR = 2.42), dyslipidemia (OR = 1.78) and TT  12 nmol/L (OR = 1.77); and the sexual sub-component was associated with high blood pressure (OR = 2.94).Although the AMS test is related to low levels of testosterone, it is also of some limited use for diagnosing hypogonadism because it has low specificity and is influenced by pathologies that are frequent during ageing.