6533b7d2fe1ef96bd125f689

RESEARCH PRODUCT

Nerve agent simulant detection by using chromogenic triaryl methane cation probes

Salvador GilSalvador GilFélix SancenónMargarita ParraMargarita ParraAna M. CosteroAna M. CosteroRaúl GotorRaúl GotorSantiago RoyoRamón Martínez-máñez

subject

Unclassified drugInorganic chemistryBiochemistryMethanechemistry.chemical_compoundChromogenicQUIMICA ORGANICADrug DiscoveryBathochromic shiftmedicineAqueous solutionTriaryl methane cationColorimetryNerve agentAqueous solutionChromogenicChemistryChemical warfare agentOrganic ChemistryQUIMICA INORGANICAChemical warfareChemosensorTriaryl methane dyeColorimetryNaked eyemedicine.drug

description

Two triaryl methane cations have been used as probes for colorimetric detection of nerve agent simulants. Buffered mixed aqueous solutions of 1 and 2 showed bathochromic shifts in the presence of DCNP (diethylcyanophosphonate) and DCP (diethylchlorophosphate). The colour modulation can be observed to the naked eye. Appropriate mechanisms for the recognition event are proposed. © 2012 Elsevier Ltd.

10.13039/501100004837https://dx.doi.org/10.1016/j.tet.2012.07.091