6533b7d2fe1ef96bd125f817
RESEARCH PRODUCT
Mechanism for polarized recombination in Streptomyces.
A. CarereG. Sermontisubject
GeneticsRecombination GeneticPolarity (international relations)biologyStereochemistryChromosome MappingHistidine biosynthesisbiology.organism_classificationStreptomycesModels BiologicalStreptomycesGeneticsHistidineCrossing Over GeneticAlleleMolecular BiologyRecombinationHistidineCrosses Geneticdescription
Recombination between pairs of mutations in a cluster of seven cistrons controlling histidine biosynthesis is highly polarized. The polarity is opposite at the opposite ends of the region. In experiments involving three his mutations it has been shown that recombination is the result of the transfer, from one parent to the other, of a segment going from the distal selected his+ allele to the end of the region. The rate of transfer is inversely proportional to the distance of the transferred his+ allele from the end of the region, at its side. A model of the process of recombination is discussed.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 1968-06-01 | Moleculargeneral genetics : MGG |