6533b7d3fe1ef96bd12609d4

RESEARCH PRODUCT

Thermal sensation and cell adaptability

Andris Auliciems

subject

Atmospheric ScienceShock proteinsAcclimatizationmedia_common.quotation_subjectHealth Toxicology and MutagenesisScale integrationTransduction (psychology)Thermal sensationBiologyMechanotransduction CellularModels BiologicalAdaptabilityCell Physiological PhenomenaTransductionAdaptive comfortAnimalsHumansThermosensingEcosystemmedia_commonReview PaperCommunicationIndoor designEcologybusiness.industryScale (chemistry)TemperatureMolecular scale adaptationThermoreceptorsAdaptation PhysiologicalASHRAE standardsAdaptability modelCell energyGene expressionSystems biologybusinessCognitive psychology

description

Whole person adaptive comfort is discussed with reference to recent findings in molecular scale systems biology. The observations are upscaled to hypotheses relating to less traditional interpretations of thermal processes, which have new implications for indoor climate management and design. Arguments are presented for a revision of current focus, model and paradigm. The issue is seen as a problem of integrating theoretical development, conceptual modeling and as an investigation of the extent to which environments and acclimatization can be used to achieve individual fitness and health, not only at the subjective comfort level, as hitherto promoted. It is argued that there are many questions yet to be asked about adaptability before celebrating a particular adaptive state.

10.1007/s00484-013-0680-9http://dx.doi.org/10.1007/s00484-013-0680-9