6533b7d3fe1ef96bd12609ef
RESEARCH PRODUCT
Modular Approach to 9-Monosubstituted Fluorene Derivatives Using Mo(V) Reagents.
Moritz SchubertSimon TrosienSiegfried R. WaldvogelPeter Franzmannsubject
chemistry.chemical_elementFluorene010402 general chemistry01 natural sciencesBiochemistryHigh yieldingchemistry.chemical_compoundMoleculeOrganic chemistryCombinatorial Chemistry TechniquesPhysical and Theoretical ChemistryMelatoninMolybdenumFluorenesMolecular StructureOxidative Coupling010405 organic chemistrybusiness.industryOrganic ChemistryModular design0104 chemical scienceschemistryMolybdenumReagentOxidative coupling of methaneIndicators and Reagentsbusinessdescription
Oxidative coupling using molybdenum(V) reagents provides fast access to highly functionalized 9-monosubstituted fluorenes. This synthetic approach is highly modular, is high yielding, and tolerates a variety of labile moieties, e.g. amides or iodo groups. The established protocol leads to promising precursors for pharmacologically important analogues of melatonin.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-02-25 | Organic letters |