6533b7d3fe1ef96bd12613ad

RESEARCH PRODUCT

Does dietary salt induce autoimmunity?

Ari WaismanBurkhard BecherAndrew L. Croxford

subject

610 Medicine & healthBiology10263 Institute of Experimental Immunologymedicine.disease_causeImmediate early proteinAutoimmunity1307 Cell Biology03 medical and health sciences0302 clinical medicineLow-salt dietsImmunopathology1312 Molecular BiologymedicineMolecular Biology030304 developmental biologyAutoimmune disease0303 health sciencesCell Biologymedicine.diseaseResearch Highlight3. Good healthImmunology570 Life sciences; biologyInterleukin 17030215 immunologyDietary salt

description

Two recent publications suggest that dietary salt may polarize TH17 cells and therefore increase the risk of developing autoimmune disease. Where low salt diets can readily be tested for their therapeutic effects in autoimmune disease, more work is needed to connect dietary salts with the development of immunopathology.

10.1038/cr.2013.65http://dx.doi.org/10.1038/cr.2013.65