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RESEARCH PRODUCT
Polyaminocyclodextrin nanosponges: synthesis, characterization and pH-responsive sequestration abilities
Renato NotoPaolo Lo MeoMaria Luisa SaladinoMarco RussoDelia Francesca Chillura Martinosubject
chemistry.chemical_classification010405 organic chemistryChemistryGeneral Chemical EngineeringPotentiometric titrationInorganic chemistryAnalytical chemistryProtonationGeneral ChemistryPolymerPorosimetrySettore CHIM/06 - Chimica Organica010402 general chemistry01 natural sciences0104 chemical sciencesMatrix (chemical analysis)Differential scanning calorimetryAdsorptionCyclodextrin Polyamine Nanosponge Polymer Supramolecular ChemistryHeteronuclear moleculeSettore CHIM/02 - Chimica Fisicadescription
New pH-responsive nanosponges were obtained by reacting four different polyaminocyclodextrins with heptakis-(6-bromo)-(6-deoxy)-β-cyclodextrin. The materials obtained were characterized by various techniques (FT-IR, potentiometric titration, differential scanning calorimetry (DSC), porosimetry (BET), 13C{1H} CP-MAS NMR). Their adsorption abilities at different pH values were verified towards a suitable set of model guests, and seem mainly controlled by electrostatic interactions, as a function of the protonation/charge status of the polymer matrix. By contrast, data positively point out a lesser importance assumed by the induced-fit effect, important in affecting the formation of host–guest complexes in solution. The frequency-switched Lee-Goldburg (FSLG) heteronuclear correlation solid-state NMR technique was exploited in order to assess the possible location of the guests within the polymer matrix.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2016-01-01 |