6533b7d4fe1ef96bd1261930

RESEARCH PRODUCT

In vitro cellular co-colture method to induce immunological tolerance

Giordano CCoppola APizzolanti GTomasello L

subject

co-colture lymphocytes toleranceSettore MED/13 - Endocrinologia

description

An in vitro method able to modulate peripheral blood mononuclear cells of patients with auto-immune organ-specific diseases is described. The protocol makes auto-reactive lymphocytes tolerogenic through a process of re-education in recognition of self-antigen after co-culture with heterologous and/or autologous fibroblast limbal stem cells.

http://hdl.handle.net/10447/301505