6533b7d4fe1ef96bd1261e35

RESEARCH PRODUCT

HIDRAdisk: validation of an innovative visual tool to assess the burden of hidradenitis suppurativa

Elena GuanziroliVincenzo BettoliMaria Letizia MusumeciFrancesco CusanoA. BertoldiAnnalisa PatriziFrancesca PrignanoClaudio GuarneriAlice CasariV. SaragagliaT. DeboliConcetta PotenzaL.l. ManciniA. Lo SchiavoPaolo AmerioLuca BianchiMarco ArdigòFranco RongiolettiGabriella FabbrociniChiara FranchiKetty PerisAndrea ParodiLuca StingeniValentina DiniGiuseppe PistoneA. M. OffidaniG. MalaraMarta FusanoGiuliana Gualberti

subject

MalePsychometricsVisual Analog ScaleIntraclass correlationAcne ‐ RosaceaHIDRAdiskLongitudinal StudieSeverity of Illness Index030207 dermatology & venereal diseases0302 clinical medicineQuality of lifeSurveys and QuestionnairesHidradenitis suppurativa030212 general & internal medicineLongitudinal StudiesIMPACT IMPAIRMENT VALIDITY DISEASE.HIDRAdisk Hidradenitis Suppurativa Quality of Life Validation study Visual toolValidation studyDermatology Life Quality IndexMiddle AgedhumanitiesInfectious DiseasesHIDRAdisk; Hidradenitis Suppurativa; Quality of Life; Validation study; Visual toolItalyhidradenitis suppurativa; visual analog scale; quality of LifeFemaleOriginal ArticleSettore MED/35 - MALATTIE CUTANEE E VENEREEVisual toolPsychometricHumanAdultmedicine.medical_specialtyPsychometricsVisual analogue scaleReproducibility of ResultDermatology03 medical and health sciencesYoung AdultCronbach's alphaInternal medicineSeverity of illnessmedicineHumansbusiness.industryhidradenitis suppurativaReproducibility of Resultsmedicine.diseaseQuality of Lifebusiness

description

Background: Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disease characterized by painful inflamed nodules, recurrent abscesses and fistulas located in apocrine gland–bearing body sites. The negative impact of HS on patient's quality of life (QoL) has been reported to be greater than other dermatologic conditions as psoriasis and atopic eczema, and its improvement is an important goal in disease management. Nowadays, there are no specific validated QoL instruments available for HS and generic dermatologic questionnaires are used. Objective: The objective of this study was to demonstrate the validity, reliability and responsiveness of HIDRAdisk, a new innovative tool designed for rapid assessment of HS burden and, at the same time, an intuitive graphic visualization of the measurement outcome. Methods: A multicentre, longitudinal, observational study was conducted to validate the HIDRAdisk compared with other validated questionnaires [Skindex-16, Dermatology Life Quality Index (DLQI), Work Productivity and Activity Impairment–General Health (WPAI:GH)] and to evaluate its correlation with disease severity in Italian patients with any degree of HS severity, as measured by Hurley stage and HS Physician Global Assessment (HS-PGA). Results: A total of 140 patients (59% women; mean age 34.9 ± 11.0 years) were enrolled in 27 dermatologic centres. HIDRAdisk showed a strong correlation with Skindex-16 and DLQI, and a good one with WPAI:GH (correlation coefficient: 0.7568, 0.6651 and 0.5947, respectively) and a statistically significant correlation with both Hurley stage and HS-PGA. Very good internal consistency (Cronbach coefficient >0.80; intraclass correlation coefficient >0.6), with correlation between the 10 items, good test–retest reliability (Spearman correlation coefficient, 0.8331; P < 0.0001) and responsiveness to changes were demonstrated. Conclusion: Our study shows that HIDRAdisk, a short and innovative visual HS QoL instrument, has been psychometrically validated in Italian language and it may help improve the management of HS once implemented in routine clinical practice.

yearjournalcountryeditionlanguage
2019-01-01
10.1111/jdv.15425http://hdl.handle.net/10807/168717