6533b7d4fe1ef96bd1262475
RESEARCH PRODUCT
Recurrent leishmaniasis in kidney transplant recipients: Report of 2 cases and systematic review of the literature
Simon IWissing K MDel Marmol VAntinori SRemmelink MNilufer Broeders ENortier J LCorbellino MAbramowicz DCascio Asubject
Leishmaniasis MucocutaneousVasculitisMaleVasculitiLeishmaniasiSettore MED/17 - Malattie InfettiveLeishmaniasis CutaneousAntibodies ProtozoanTransplantPolymerase Chain ReactionTongueRecurrenceHumansleishmaniasisLeishmaniasis MucocutaneouLeishmaniaTransplantationLeg UlcerLeishmaniasis CutaneouMiddle AgedKidney TransplantationInfectious DiseasesCryoglobulinemiacryogolbulinemiaLeishmaniasis VisceralFemaleHumanLeishmania donovanidescription
The characteristics of 8 episodes of leishmaniasis with atypical manifestations in 2 Italian kidney transplant recipients are analyzed and contextualized among those of 52 other episodes of leishmaniasis observed in 19 transplant recipients found through a systematic review of the international literature. In all the patients, the initial episode was visceral leishmaniasis, which was associated with mucocutaneous involvement in 2 cases. With the exception of 1 case of post kala-azar dermal leishmaniasis, 2 episodes of Leishmania endophthalmitis, and 3 episodes of mucocutaneous leishmaniasis, all the recurrences were characterized by visceral involvement. The potential role of polymerase chain reaction in monitoring the infection, the importance of a long follow-up, the potential benefit of chemoprophylaxis, and the therapeutic challenges are discussed. © 2011 John Wiley & Sons A/S.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2011-01-01 |