6533b7d4fe1ef96bd12633be

RESEARCH PRODUCT

Regional blood flow in deep structures of the brain measured in acute cat experiments by means of a new beta-sensitive semiconductor needle detector.

M. BrockM. BrockC. W. Sem JacobsenDavid H. Ingvar

subject

Materials scienceMetabolic Clearance RateSolid-stateBlood PressureBrain EdemaCortex (anatomy)medicineAnimalsBeta (finance)Cerebral CortexRadioisotopesIsotopebusiness.industryGeneral NeuroscienceDetectorKryptonBlood flowSemiconductormedicine.anatomical_structureCerebral blood flowSemiconductorsRegional Blood FlowCerebrovascular CirculationCatsbusinessNuclear medicineBlood Flow VelocityBiomedical engineering

description

Regional cerebral blood flow was measured by means of isotope clearance with a new type of solid state beta-sensitive needle detector (diameter 0.9 mm) introduced into the brain tissue in acute cat experiments. The flow values obtained within the cortex were compared with values recorded above the same cortical region with the same needle detector, or with a small GM-tube. The insertion of the needle detector into the brain tissue gave rise to injury (checked histologically) which deformed the clearance curves in a manner suggesting that the normal circulation had been destroyed within the tissue from which the measurements were made.

10.1007/bf00240358https://pubmed.ncbi.nlm.nih.gov/5598821