Reaction of 4,5-diamino-1,6-dihydropyrimidin-6-ones with two equivalents of chalcones

6533b7d5fe1ef96bd1263b05

RESEARCH PRODUCT

Reaction of 4,5-diamino-1,6-dihydropyrimidin-6-ones with two equivalents of chalcones

Adolfo Sánchez Norbert Hanold Jairo Quiroga Herbert Meier Rodolfo Moreno Manuel Nogueras Braulio Insuasty Monica Ramos

subject

Diffraction Equivalent Chemistry Organic Chemistry Medicinal chemistry

description

The reaction of 4,5-diamino-1,6-dihydropyrimidin-6-ones 1 with two equivalents of the chalcones 2 leads in an acidic medium to the formation of the 2,3,6,7-tetrahydro-1H-pyrimido[4,5-b][1,4]diazepin-6-one derivatives 3a-d. The structure elucidation of the products is based on nmr measurements and an X-ray diffraction.

year	journal	country	edition	language
1995-07-01	Journal of Heterocyclic Chemistry

https://doi.org/10.1002/jhet.5570320423

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