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RESEARCH PRODUCT

Influence of habitual dairy food intake on LDL cholesterol in a population-based cohort

Silvio BuscemiGiuseppe RosafioCarola BuscemiCristiana RandazzoRosalia CaldarellaRaffaele Ivan CincioneSalvatore MaestriFabio GalvanoWalter CurrentiAntonio M. BorzìFrancesco MeliDavide CorleoMarcello CiaccioAnna Maria BarilePaolo Murabito

subject

MaleAdultPopulationlcsh:TX341-641Blood PressureLongitudinal StudieBody fat percentageArticleBody Mass IndexLDLCohort StudiesDairychemistry.chemical_compoundAnimal scienceCheeseSurveys and QuestionnairesMedicineAnimalsHumansLongitudinal StudiesSettore MED/49 - Scienze Tecniche Dietetiche ApplicateeducationSicilyeducation.field_of_study...Nutrition and Dieteticsbusiness.industryCholesterolWaist-Hip RatioAnimalFeeding BehaviorCholesterol LDLAnthropometryMiddle AgedRicottaBlood pressureCholesterolMilkchemistryCohortFemalelipids (amino acids peptides and proteins)Glycated hemoglobinDairy ProductsbusinessBody mass indexlcsh:Nutrition. Foods and food supplyFood Science

description

Background: Cholesterol has a pivotal role in human physiology, exerting both structural and functional activity. However, higher blood cholesterol levels, especially low-density lipoprotein cholesterol (LDL-C), are a major cardiovascular risk factor. Therefore, special attention has been given to the effect of dietary factors in influencing LDL-C blood levels. In particular, much research has focused on dairy products, since they are a main component of different dietary patterns worldwide. A large body of evidence did not support the hypothesis that dairy products significantly increase circulating LDL-C, but no definitive data are available. Hence, we aimed to assess the relationships among LDL-C, habitual dairy food intake and anthropometric variables in a cohort representative of the general population in a Mediterranean area. Methods: We evaluated 802 healthy adults included in the ABCD_2 (Alimentazione, Benessere Cardiovascolare e Diabete) study (ISRCTN15840340), a longitudinal observational single-center study of a cohort representative of the general population of Palermo, Sicily. The habitual intake of dairy products was assessed with a validated food frequency questionnaire, and LDL-C serum levels and several anthropometric parameters were measured. Results: The group with high LDL-C serum concentrations (≥130 vs. &lt

10.3390/nu13020593http://hdl.handle.net/20.500.11769/506311