6533b7d5fe1ef96bd1265113

RESEARCH PRODUCT

Aurintricarboxylic acid as a nuclease inhibitor in fungal protoplasts

Federico UruburuDaniel RamónEduardo VicenteSergi Ferrer

subject

NucleaseSaccharomyces cerevisiaeBiologyPenicillium chrysogenumbiology.organism_classificationMicrobiologyIn vitrochemistry.chemical_compoundTransformation (genetics)chemistryBiochemistryIn vivoAurintricarboxylic acidGeneticsbiology.proteinMolecular BiologyDNA

description

Aurintricarboxylic acid (ATA), a potent nuclease inhibitor, has been shown to prevent foreign DNA degradation in transformation of Penicillium chrysogenum and Saccharomyces cerevisiae. ATA may be useful not only in vitro but also in vivo.

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