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RESEARCH PRODUCT
Kawasaki disease epidemic: pitfalls
Romina GallizziGiovanni Battista PajnoGiovanni Corsellosubject
2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Inflammatory responsevirusesPneumonia ViralHyperinflammatory response; Kawasaki disease; Pediatric population; SARS-CoV-2; COVID-19; Coronavirus Infections; Humans; Mucocutaneous Lymph Node Syndrome; Pandemics; Pneumonia Viral; SARS-CoV-2; BetacoronavirusMucocutaneous Lymph Node SyndromeVirusBetacoronavirusSettore MED/38 - Pediatria Generale E SpecialisticaMedicineHumansPediatric populationViralskin and connective tissue diseasesPandemicsViral etiologyKawasaki diseasebusiness.industrySARS-CoV-2lcsh:RJ1-570COVID-19lcsh:PediatricsPneumoniamedicine.diseaseHyperinflammatory responseImmunologyEtiologyCommentaryKawasaki diseasebusinessCoronavirus InfectionsPediatric populationdescription
AbstractRecent reports have described in the pediatric population a new type of hyperinflammatory response manifested following contact with SARS-CoV-2, with some of the clinical features attributable to Kawasaki disease (KD). The purpose of this commentary is to remark on a possible recent association between SARS-CoV-2 and KD. Although today little is known about the etiology of KD, the most accepted hypothesis is that of a probable viral etiology, therefore, even the SARS-CoV-2 virus could trigger, in genetically predisposed subjects, an exaggerated inflammatory response that is clinically evident like the one described in KD.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-08-27 | Italian Journal of Pediatrics |