Dual Hydrogen Bond - Enamine Catalysis Enables a Direct Enantioselective Three-Component Domino Reaction

6533b7d5fe1ef96bd12652e8

RESEARCH PRODUCT

Dual Hydrogen Bond - Enamine Catalysis Enables a Direct Enantioselective Three-Component Domino Reaction

ÁDám Madarász Petri M. Pihko Imre Pápai Hasibur Rahaman

subject

Hydrogen bond catalysis Component (thermodynamics)Hydrogen bond Chemistry Enantioselective synthesis General Medicine General Chemistry Catalysis Catalysis Enamine chemistry.chemical_compound Cascade reaction Organocatalysis Organic chemistry ta116

description

A dual system, composed of an enantioselective enamine catalyst and a multiple-hydrogen-bond catalyst achieves the three-component enantioselective aldehyde—nitroalkene—aldehyde domino reaction using either two similar or two different aldehydes.

year	journal	country	edition	language
2011-05-23	Angewandte Chemie Intermational Edition

10.1002/anie.201101835 http://juuli.fi/Record/0050395511

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