6533b7d6fe1ef96bd1265986
RESEARCH PRODUCT
Random Forest Analysis: A New Approach for Classification of Beta Thalassemia
S MassimilianoMariangela SciandraM Aureliosubject
congenital hereditary and neonatal diseases and abnormalitiesPediatricsmedicine.medical_specialtybusiness.industryThalassemiaBeta thalassemiamedicine.diseaseRandom foresthemic and lymphatic diseasesExpert opinionTransfusion statusmedicineTransfusion therapybusinessdescription
In recent years, Thalassemia care providers started classifying patients as transfusion-dependent-Thalassemia (TDT) or non-transfusion-dependent-Thalassemia (NTDT) owing to the established role of transfusion therapy in defining the clinical complication profile, although this classification was also based on expert opinion and is limited by reliance on patients’current transfusion status. Starting from a vast set of variables indicating severity phenotype, through the use of both classification and clustering techniques we want to explore the presence of two (TDT vs NTDT) or more clusters, in order to approaching to a new definition for the classification of Beta-Thalassemia in Thalassemia Syndromes (TS).
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2020-01-01 | SSRN Electronic Journal |