6533b7d6fe1ef96bd1265d11

RESEARCH PRODUCT

Different types of intestinal atresia in identical twins

Enrico De GraziaMaria Rita DipacePieralba CatalanoAnna Maria CarusoMarcello Cimador

subject

AdultAbortion Habitualcongenital hereditary and neonatal diseases and abnormalitiesIntestinal AtresiaPhysiologySingle geneInfant Premature DiseasesAnastomosisModels BiologicalDuodenal atresiaDuodenal atresia intestinal atresiamonozygotic twins newbornnewbornPregnancyDiseases in TwinsmedicineHumansInfant Very Low Birth Weightintestinal malformationGeneLaparotomybusiness.industrySettore MED/20 - Chirurgia Pediatrica E InfantileAnastomosis SurgicalIntestinal atresiaInfant NewborntwinsJejunal DiseasesTwins MonozygoticGeneral Medicinemedicine.diseaseJejunumJejunal atresiaPediatrics Perinatology and Child HealthFemaleParenteral Nutrition TotalSurgeryDuodenal ObstructionIdentical twinsbusinessInfant PrematureIntestinal Volvulus

description

The authors present a previously unreported association of different types of intestinal atresia in identical low-birth-weight twins. Both babies were affected by duodenal atresia, associated in the first case with a complete mucosal duodenal membrane and in the second one with an "apple-peel" jejunal atresia. These occurrences may suggest that they were either the consequence of linkage of 2 genes or a pleiotropic expression of a single gene responsible for such rare conditions.

yearjournalcountryeditionlanguage
2008-01-01Journal of Pediatric Surgery
https://doi.org/10.1016/j.jpedsurg.2008.08.068