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RESEARCH PRODUCT
Comparison of clinical characteristics between coronavirus disease 2019 pneumonia and community-acquired pneumonia
Qizhong XuSong LiuJuncai TianXuewen HouLingli MaoMaoren Wangsubject
AdultMaleChinamedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Pneumonia Viral030204 cardiovascular system & hematologySeverity of Illness IndexBetacoronavirus03 medical and health sciences0302 clinical medicineCommunity-acquired pneumoniaInternal medicineSeverity of illnessPandemicmedicineHumans030212 general & internal medicinePandemicsAgedRetrospective StudiesbiologySARS-CoV-2business.industryCase-control studyCOVID-19Retrospective cohort studyGeneral MedicineMiddle AgedPrognosisbiology.organism_classificationmedicine.diseaseCommunity-Acquired InfectionsPneumoniaCase-Control StudiesFemaleCoronavirus InfectionsbusinessBetacoronavirusdescription
Coronavirus disease 2019 (COVID-19) has high morbidity and mortality, and spreads rapidly in the community to result in a large number of infection cases. This study aimed to compare clinical features in adult patients with coronavirus disease 2019 (COVID-19) pneumonia to those in adult patients with community-acquired pneumonia (CAP).Clinical presentations, laboratory findings, imaging features, complications, treatment and outcomes were compared between patients with COVID-19 pneumonia and patients with CAP. The study group of patients with COVID-19 pneumonia consisted of 120 patients. One hundred and thirty-four patients with CAP were enrolled for comparison.Patients with COVID-19 pneumonia had lower levels of abnormal laboratory parameters (white blood cell count, lymphocyte count, procalcitonin level, erythrocyte sedimentation rate and C-reactive protein level) and more extensive radiographic involvement. More severe respiratory compromise resulted in a higher rate of intensive care unit admission, acute respiratory distress syndrome (ARDS) and mechanical ventilation (36% vs 15%, 34% vs 15% and 32% vs 12%, respectively; allLower levels of abnormal laboratory parameters, more extensive radiographic involvement, more severe respiratory compromise, and higher rates of ICU admission, ARDS and mechanical ventilation are key characteristics that distinguish patients with COVID-19-associated pneumonia from patients with CAP.
year | journal | country | edition | language |
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2020-09-29 | Current Medical Research and Opinion |