6533b7d6fe1ef96bd1266794
RESEARCH PRODUCT
Rapid malignant progression of an intraparenchymal choroid plexus papillomas
Luca RuggeriRosario MaugeriCesare GambadoroNicola AlberioRoberto BattagliaRaffaele AlessandrelloFrancesco NobileDomenico Gerardo IacopinoGiovanni CinquemaniRita LipaniGiovanni Urricosubject
Pathologymedicine.medical_specialtyChoroid plexus atypical papillomaWorld health03 medical and health sciences0302 clinical medicineCarcinomaMedicinechoroid plexus papillomasSettore MED/27 - Neurochirurgiabusiness.industrychoroid plexus carcinomaGeneral Neurosurgery: Case Reportmalignant progressionChoroid plexus carcinomamedicine.diseaseChoroid plexus papilloma030220 oncology & carcinogenesischoroid plexus papillomaPapillomaSurgeryChoroid plexusNeurology (clinical)Histological gradesMalignant progressionbusinessWorld Health Organization classification030217 neurology & neurosurgerydescription
Background: Choroid plexus tumors (CPTs) are rare neoplasms accounting for only 0.3-0.6% of all brain tumors in adults and 2-5% in children. The World Health Organization (WHO) classification describes three histological grades: grade I is choroid plexus papilloma (CPP), grade II is atypical papilloma, and grade III is the malignant form of carcinoma. In adults, CPTs rarely have a supratentorial localization. Case Description: Here we report a very rare case of an intraparenchymal parietal CPP with a rapid histological transition from grade I to grade III WHO in a 67-year-old man, in <7 months. Conclusion: Because of the rarity of these oncotypes, descriptions of each new case are useful, mostly to consider this diagnostic entity in extraventricular brain tumors of adults, despite an unusual location.
| year | journal | country | edition | language |
|---|---|---|---|---|
| 2018-07-01 | Surgical Neurology International |