6533b7d6fe1ef96bd1266e3b

RESEARCH PRODUCT

Vergleich der Wertigkeit von Magnetresonanztomographie und Computertomographie bei Patienten mit Nelson-Syndrom

Stiebler HKlingmüller DAllmendinger SChrist FKersjes WBockisch A

subject

Hypophysectomybusiness.industrymedicine.medical_treatmentOptic chiasmNelson SyndromeInfundibulummedicine.anatomical_structureTumour developmentCavernous sinusmedicineRadiology Nuclear Medicine and imagingBilateral adrenalectomyTomographyNuclear medicinebusiness

description

The hypophyses of 13 patients with Nelson syndrome following bilateral adrenalectomy were examined by MRI and CT. Diffuse enlargement of the hypophysis was demonstrated in 8 patients by CT and in 9 by MRI. Compared with CT, MRI provides better demonstration of tumour development, such as abnormal convexity of the cranial margin of the hypophysis (MRI 4/13, CT 1/13), displacement of the infundibulum (MRI 4/13, CT 0/13) or optic chiasm (MRI 2/13, CT 0/13). MRI also provides diagnostically important differentiation between scar tissue and recurrence of tumour following hypophysectomy (MRI 1/3, CT 0/3) and more accurate demonstration of infiltration of the cavernous sinus (MRI 4/13, CT 2/13). CT is superior only in showing the floor of the sella. MRI is the method of choice for imaging in cases of Nelson syndrome.

https://doi.org/10.1055/s-2008-1032858